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    thi201 phosphomethylpyrimidine kinase Thi201 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541373, updated on 18-Sep-2024

    Summary

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    Official Symbol
    thi201
    Official Full Name
    phosphomethylpyrimidine kinase Thi201
    Primary source
    PomBase:SPBP8B7.18c
    Locus tag
    SPOM_SPBP8B7.18C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See thi201 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3667950..3669924, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase Dbp2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphomethylpyrimidine kinase Thi20 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene histone H2A-H2B chaperone, FACT complex subunit Spt16 Neighboring gene RNA methyltransferase Nop2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    2. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydroxymethylpyrimidine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphomethylpyrimidine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in thiamine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in thiamine diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    phosphomethylpyrimidine kinase Thi201

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3667950..3669924 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022446.3 → NP_596525.1  phosphomethylpyrimidine kinase Thi201 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596525.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94266
      Conserved Domains (3) summary
      COG0351
      Location:35 → 314
      ThiD; Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Coenzyme transport and metabolism]
      COG0819
      Location:321 → 539
      TenA; Thiaminase [Coenzyme transport and metabolism]
      PRK14713
      Location:32 → 535
      PRK14713; multifunctional hydroxymethylpyrimidine phosphokinase/4-amino-5-aminomethyl-2-methylpyrimidine hydrolase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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