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    msy1 MS ion channel protein 1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539051, updated on 18-Sep-2024

    Summary

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    Official Symbol
    msy1
    Official Full Name
    MS ion channel protein 1
    Primary source
    PomBase:SPCC1183.11
    Locus tag
    SPOM_SPCC1183.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPCC31H12.01
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    Genomic context

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    See msy1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (618848..623222)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene wtf antidote-like meiotic drive suppressor Wtf10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transporter mug73 Neighboring gene RNA-binding protein mlo1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanosensitive channels Msy1 and Msy2 are required for maintaining organelle integrity upon hypoosmotic shock in Schizosaccharomyces pombe. Nakayama Y, et al. FEMS Yeast Res, 2014 Sep. PMID 25041276
    2. Organellar mechanosensitive channels in fission yeast regulate the hypo-osmotic shock response. Nakayama Y, et al. Nat Commun, 2012. PMID 22910366
    3. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
    4. SR protein kinases promote splicing of nonconsensus introns. Lipp JJ, et al. Nat Struct Mol Biol, 2015 Aug. PMID 26167880
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Msy1 and Msy2 regulate intracellular Ca(2+) and cell volume for survival upon hypo-osmotic shock.
      Title: Organellar mechanosensitive channels in fission yeast regulate the hypo-osmotic shock response.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding NAS
    Non-traceable Author Statement
    more info
    		  
    enables stretch-activated, monoatomic cation-selective, calcium channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in calcium ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in cell volume homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intracellular calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular calcium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in membrane ISM
    Inferred from Sequence Model
    more info
    		  
    is_active_in perinuclear endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MS ion channel protein 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      618848..623222
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022886.3 → NP_587894.1  MS ion channel protein 1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_587894.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74839
      Conserved Domains (2) summary
      COG0668
      Location:596 → 787
      MscS; Small-conductance mechanosensitive channel [Cell wall/membrane/envelope biogenesis]
      pfam00924
      Location:602 → 795
      MS_channel; Mechanosensitive ion channel
    Nucleotide Protein
    Heading Accession and Version

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