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    cdc7 serine/threonine protein kinase SIN pathway Cdc7 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540660, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cdc7
    Official Full Name
    serine/threonine protein kinase SIN pathway Cdc7
    Primary source
    PomBase:SPBC21.06c
    Locus tag
    SPOM_SPBC21.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    its10; pld1
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    Genomic context

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    See cdc7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    11
    Sequence:
    Chromosome: II; NC_003423.3 (3222351..3226505, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene EVE domain (PUA-related) protein, implicated in tRNA metabolism (possible RNA binding domain associated with tRNA methyltransferases) Neighboring gene V-type ATPase inhibitor and disassembly protein linked to MTOR Neighboring gene mediator complex subunit Med8 Neighboring gene Ras1-Scd pathway protein Ral2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase Ppk24

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of functional domains within the septation initiation network kinase, Cdc7. Mehta S, et al. J Biol Chem, 2006 Apr 14. PMID 16469735
    2. Regulation of chromosome dynamics by Hsk1/Cdc7 kinase. Matsumoto S, et al. Biochem Soc Trans, 2013 Dec. PMID 24256280
    3. The Schizosaccharomyces pombe Cdc7 protein kinase required for septum formation is a client protein of Cdc37. Liang J, et al. Eukaryot Cell, 2007 Jul. PMID 17496123, Free PMC Article
    4. The cdc7 protein kinase is a dosage dependent regulator of septum formation in fission yeast. Fankhauser C, et al. EMBO J, 1994 Jul 1. PMID 8039497, Free PMC Article
    5. Asymmetric segregation on spindle poles of the Schizosaccharomyces pombe septum-inducing protein kinase Cdc7p. Sohrmann M, et al. Genes Dev, 1998 Jan 1. PMID 9420333, Free PMC Article

    See all (64) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of mitotic division septum assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in septation initiation signaling EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in septation initiation signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in new mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in old mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine protein kinase SIN pathway Cdc7

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3222351..3226505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022261.3 → NP_596340.1  serine/threonine protein kinase SIN pathway Cdc7 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596340.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P41892
      Conserved Domains (2) summary
      smart00220
      Location:10 → 259
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06627
      Location:10 → 259
      STKc_Cdc7_like; Catalytic domain of Cell division control protein 7-like Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version

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