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    atg12 autophagy-associated ubiquitin-like modifier Atg12 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542368, updated on 18-Sep-2024

    Summary

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    Official Symbol
    atg12
    Official Full Name
    autophagy-associated ubiquitin-like modifier Atg12
    Primary source
    PomBase:SPAC1783.06c
    Locus tag
    SPOM_SPAC1783.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    apg12
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    Genomic context

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    See atg12 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (2199327..2200120, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene CENP-P family protein Fta2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CENP-A chaperone, CHD family Hrp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA-binding transcription factor, oxidative stress-responsive Pap1/Caf3 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation. Mukaiyama H, et al. Microbiology (Reading), 2009 Dec. PMID 19778961
    2. Global analysis of fission yeast mating genes reveals new autophagy factors. Sun LL, et al. PLoS Genet, 2013. PMID 23950735, Free PMC Article
    3. Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1. Kilchert C, et al. Cell Rep, 2015 Dec 22. PMID 26670050, Free PMC Article
    4. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
    5. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to Atg8-family ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tag activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in autophagosome maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in piecemeal microautophagy of the nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Atg12-Atg5-Atg16 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in autophagosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in phagophore assembly site membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    autophagy-associated ubiquitin-like modifier Atg12

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2199327..2200120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019093.3 → NP_593661.1  autophagy-associated ubiquitin-like modifier Atg12 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593661.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9US24
      Conserved Domains (1) summary
      pfam04110
      Location:46 → 132
      APG12; Ubiquitin-like autophagy protein Apg12
    Nucleotide Protein
    Heading Accession and Version

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