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    cdc1 DNA polymerase delta small subunit Cdc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542083, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cdc1
    Official Full Name
    DNA polymerase delta small subunit Cdc1
    Primary source
    PomBase:SPAC27E2.05
    Locus tag
    SPOM_SPAC27E2.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mis1
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    Genomic context

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    See cdc1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (4015050..4016557)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene protein mug155 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene methionine--tRNA (Met) ligase Neighboring gene ncRNA Neighboring gene Golgi 4,6-pyruvylated galactose (PvGal) residue biosynthesis protein Pvg2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The C-terminal zinc finger of the catalytic subunit of DNA polymerase delta is responsible for direct interaction with the B-subunit. Sanchez Garcia J, et al. Nucleic Acids Res, 2004. PMID 15173383, Free PMC Article
    2. Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis. Sanchez Garcia J, et al. BMC Mol Biol, 2009 Aug 17. PMID 19686603, Free PMC Article
    3. RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe. Smialowska A, et al. Biochem Biophys Res Commun, 2014 Feb 7. PMID 24462781
    4. Mapping and mutation of the conserved DNA polymerase interaction motif (DPIM) located in the C-terminal domain of fission yeast DNA polymerase delta subunit Cdc27. Gray FC, et al. BMC Mol Biol, 2004 Dec 3. PMID 15579205, Free PMC Article
    5. Mitotic replication initiation proteins are not required for pre-meiotic S phase. Forsburg SL, et al. Nat Genet, 2000 Jul. PMID 10888871

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The E2, J1, J16, J21, J17 and J6 mutations disrupt Cdc1 interactions with both Pol3 and Cdc27 in two hybrid-assays.
      Title: Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA strand elongation involved in DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA strand elongation involved in DNA replication IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in DNA synthesis involved in UV-damage excision repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic DNA replication lagging strand elongation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mitotic DNA replication leading strand elongation NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in premeiotic DNA replication IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    part_of delta DNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of delta DNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    DNA polymerase delta small subunit Cdc1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4015050..4016557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019837.2 → NP_594406.1  DNA polymerase delta small subunit Cdc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594406.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P87324
      Conserved Domains (2) summary
      COG1311
      Location:1 → 460
      HYS2; Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B [Replication, recombination and repair]
      cd07387
      Location:185 → 449
      MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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