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    cwf4 protein Cwf4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540328, updated on 22-Jun-2024

    Summary

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    Gene symbol
    cwf4
    Gene description
    protein Cwf4
    Locus tag
    SPOM_SPBC31F10.11C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    syf3
    Old locus tag
    SPBC31F10.11c
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    Genomic context

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    See cwf4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3770856..3773149, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene armadillo-type fold protein, zf-MYND type zinc finger protein, Mub1-Rad6-Ubr2 ubiquitin ligase complex Mub1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA-binding protein Tma20 Neighboring gene histone chaperone Hip1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Nrl1 Domains Responsible for Interactions with RNA-Processing Factors and Regulation of Nrl1 Function by Phosphorylation. Mikolaskova B, et al. Int J Mol Sci, 2021 Jun 29. PMID 34209806, Free PMC Article
    2. Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. McDonald WH, et al. Mol Cell Biol, 1999 Aug. PMID 10409726, Free PMC Article
    3. Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. Ohi MD, et al. RNA, 2002 Jun. PMID 12088152, Free PMC Article
    4. Structure of a yeast spliceosome at 3.6-angstrom resolution. Yan C, et al. Science, 2015 Sep 11. PMID 26292707
    5. The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast. Aronica L, et al. Nucleic Acids Res, 2016 Feb 29. PMID 26682798, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spliceosomal complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Prp19 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Prp19 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of U2-type catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U2-type prespliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of post-mRNA release spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein Cwf4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3770856..3773149 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022494.3 → NP_596573.1  protein Cwf4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596573.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P87312
      Conserved Domains (4) summary
      pfam02184
      Location:185 → 216
      HAT; HAT (Half-A-TPR) repeat
      smart00386
      Location:84 → 116
      HAT; HAT (Half-A-TPR) repeats
      COG5107
      Location:58 → 561
      RNA14; Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification]
      sd00006
      Location:73 → 98
      TPR; TPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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