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    swi2 DNA recombination mediator Swi2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361456, updated on 22-Jun-2024

    Summary

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    Gene symbol
    swi2
    Gene description
    DNA recombination mediator Swi2
    Locus tag
    SPOM_SPAC1142.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC17G6.20c
    Old locus tag
    SPAC1142.03c
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    Genomic context

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    See swi2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3629015..3631458, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein Rqc1 Neighboring gene ncRNA Neighboring gene SGT2 family TPR repeat-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Noc complex Noc2 family subunit Neighboring gene 5S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching. Maki T, et al. Nucleic Acids Res, 2023 May 8. PMID 36951094, Free PMC Article
    2. An improved strategy for tandem affinity purification-tagging of Schizosaccharomyces pombe genes. Cipak L, et al. Proteomics, 2009 Oct. PMID 19750511, Free PMC Article
    3. Heterochromatin regulates cell type-specific long-range chromatin interactions essential for directed recombination. Jia S, et al. Cell, 2004 Nov 12. PMID 15537537
    4. The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching. Aguilar-Arnal L, et al. EMBO J, 2008 Apr 9. PMID 18354497, Free PMC Article
    5. Fission yeast Swi5/Sfr1 and Rhp55/Rhp57 differentially regulate Rhp51-dependent recombination outcomes. Akamatsu Y, et al. EMBO J, 2007 Mar 7. PMID 17304215, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching.
      Title: Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in donor selection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in gene conversion at mating-type locus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in gene conversion at mating-type locus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Swi5-Swi2 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of mating-type region heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    DNA recombination mediator Swi2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3629015..3631458 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019690.3 → NP_001018264.1  DNA recombination mediator Swi2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_001018264.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10668
      UniProtKB/TrEMBL
      H2FH12
    Nucleotide Protein
    Heading Accession and Version

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