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    MRX18 17-beta-hydroxysteroid dehydrogenase-like protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852346, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MRX18
    Official Full Name
    17-beta-hydroxysteroid dehydrogenase-like protein
    Primary source
    SGD:S000000260
    Locus tag
    YBR056W
    See related
    AllianceGenome:SGD:S000000260; FungiDB:YBR056W; VEuPathDB:YBR056W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable glucan endo-1,6-beta-glucosidase activity. Predicted to be involved in cellular glucan metabolic process and glucan catabolic process. Located in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See MRX18 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (347879..349384)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene U4/U6-U5 snRNP complex subunit PRP6 Neighboring gene tRNA-Leu Neighboring gene tRNA-Gln Neighboring gene Mnc1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae. Chauhan N, et al. Yeast, 2020 Jan. PMID 31758572
    2. Intermembrane space proteome of yeast mitochondria. Vögtle FN, et al. Mol Cell Proteomics, 2012 Dec. PMID 22984289, Free PMC Article
    3. Pex19 is involved in importing dually targeted tail-anchored proteins to both mitochondria and peroxisomes. Cichocki BA, et al. Traffic, 2018 Oct. PMID 30033679
    4. Molecular Connectivity of Mitochondrial Gene Expression and OXPHOS Biogenesis. Singh AP, et al. Mol Cell, 2020 Sep 17. PMID 32877643
    5. Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins. Hesselberth JR, et al. Genome Biol, 2006. PMID 16606443, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables beta-glucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucan endo-1,6-beta-glucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in glucan catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm HDA PubMed 
    located_in cytosol HDA PubMed 
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial intermembrane space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    17-beta-hydroxysteroid dehydrogenase-like protein
    NP_009612.1
    • Putative glycoside hydrolase of the mitochondrial intermembrane space

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      347879..349384
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178404.1 → NP_009612.1  TPA: 17-beta-hydroxysteroid dehydrogenase-like protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009612.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ55, P38081
      UniProtKB/TrEMBL
      A6ZKZ9, B3LN93, C7GSU2, D3UEF1, G2W961, N1P813
      Conserved Domains (1) summary
      COG2730
      Location:25 → 485
      BglC; Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38081.1

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