U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    prp22 ATP-dependent RNA helicase, spliceosomal Prp22 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542978, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    prp22
    Official Full Name
    ATP-dependent RNA helicase, spliceosomal Prp22
    Primary source
    PomBase:SPAC10F6.02c
    Locus tag
    SPOM_SPAC10F6.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See prp22 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1206812..1210579, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene sulfite reductase beta subunit Sir1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CTP synthase Cts1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Early splicing functions of fission yeast Prp16 and its unexpected requirement for gene Silencing is governed by intronic features. Vijayakumari D, et al. RNA Biol, 2019 Jun. PMID 30810475, Free PMC Article
    2. The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast. Aronica L, et al. Nucleic Acids Res, 2016 Feb 29. PMID 26682798, Free PMC Article
    3. A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast. Bayne EH, et al. Genome Biol, 2014. PMID 25274039, Free PMC Article
    4. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Carnahan RH, et al. Eukaryot Cell, 2005 Mar. PMID 15755920, Free PMC Article
    5. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Livesay SB, et al. Eukaryot Cell, 2013 Nov. PMID 24014766, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spliceosomal complex disassembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ATP-dependent RNA helicase, spliceosomal Prp22

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1206812..1210579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018650.3 → NP_593253.1  ATP-dependent RNA helicase, spliceosomal Prp22 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593253.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42643
      Conserved Domains (7) summary
      smart00490
      Location:737 → 841
      HELICc; helicase superfamily c-terminal domain
      smart00487
      Location:506 → 692
      DEXDc; DEAD-like helicases superfamily
      smart00847
      Location:909 → 992
      HA2; Helicase associated domain (HA2) Add an annotation
      COG1185
      Location:1 → 441
      Pnp; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Translation, ribosomal structure and biogenesis]
      cd00046
      Location:527 → 666
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd05684
      Location:207 → 287
      S1_DHX8_helicase; S1_DHX8_helicase: The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced ...
      pfam07717
      Location:1026 → 1125
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials