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    OCA4 Oca4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850457, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OCA4
    Official Full Name
    Oca4p
    Primary source
    SGD:S000000691
    Locus tag
    YCR095C
    See related
    AllianceGenome:SGD:S000000691; FungiDB:YCR095C; VEuPathDB:YCR095C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See OCA4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (288170..289258, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene CCR4-NOT core subunit CDC39 Neighboring gene aminophospholipid translocase regulatory protein CDC50 Neighboring gene uncharacterized protein Neighboring gene homeodomain mating type protein a2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A complex-based reconstruction of the Saccharomyces cerevisiae interactome. Wang H, et al. Mol Cell Proteomics, 2009 Jun. PMID 19176519, Free PMC Article
    2. Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms. Romá-Mateo C, et al. Mol Genet Genomics, 2011 Apr. PMID 21409566
    3. Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Kushner DB, et al. Proc Natl Acad Sci U S A, 2003 Dec 23. PMID 14671320, Free PMC Article
    4. Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor. Fong CS, et al. FEMS Yeast Res, 2008 May. PMID 18205808
    5. Host co-factors of the retrovirus-like transposon Ty1. Risler JK, et al. Mob DNA, 2012 Aug 2. PMID 22856544, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 

    General protein information

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    Preferred Names
    Oca4p
    NP_010019.1
    • Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      288170..289258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178801.1 → NP_010019.1  TPA: Oca4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010019.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VR95, P25366
      UniProtKB/TrEMBL
      B3LUE7, B5VF25, C7GUV5, C8Z4I1, N1P643
      Conserved Domains (2) summary
      COG2365
      Location:52 → 349
      Oca4; Protein tyrosine/serine phosphatase [Signal transduction mechanisms]
      cd17662
      Location:2 → 198
      PFA-DSP_Oca4; atypical dual specificity phosphatases similar to oxidant-induced cell-cycle arrest protein 4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25366.1

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