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    COG5 Golgi transport complex subunit COG5 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855676, updated on 2-Nov-2024

    Summary

    Official Symbol
    COG5
    Official Full Name
    Golgi transport complex subunit COG5
    Primary source
    SGD:S000004996
    Locus tag
    YNL051W
    See related
    AllianceGenome:SGD:S000004996; FungiDB:YNL051W; VEuPathDB:YNL051W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    API4; COD4
    Summary
    Involved in cytoplasm to vacuole targeting by the Cvt pathway and intra-Golgi vesicle-mediated transport. Located in cytosol. Part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIi. Orthologous to human COG5 (component of oligomeric golgi complex 5). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See COG5 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (532659..533870)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene tyrosine/serine/threonine protein phosphatase MSG5 Neighboring gene cytochrome c oxidase subunit Va Neighboring gene uncharacterized protein Neighboring gene COPII subunit SFB2

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasm to vacuole targeting by the Cvt pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Golgi transport complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in cytosol HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Golgi transport complex subunit COG5
    NP_014347.1
    • Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      532659..533870
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182890.1NP_014347.1  TPA: Golgi transport complex subunit COG5 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014347.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1C8, P53951
      UniProtKB/TrEMBL
      B3LNR2, B5VQZ0, C8ZGH7, N1NY12
      Conserved Domains (1) summary
      pfam10392
      Location:14146
      COG5; Golgi transport complex subunit 5