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    YAP3 Yap3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856377, updated on 29-Jun-2024

    Summary

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    Gene symbol
    YAP3
    Gene description
    Yap3p
    Primary source
    FungiDB:YHL009C
    Locus tag
    YHL009C
    See related
    SGD:S000001001; AllianceGenome:SGD:S000001001; VEuPathDB:YHL009C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA-binding transcription factor activity. Involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See YAP3 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (84068..85060, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene ribose phosphate diphosphokinase subunit PRS3 Neighboring gene Etp1p Neighboring gene tRNA-Val Neighboring gene gag protein Neighboring gene gag-pol fusion protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast. North M, et al. PLoS One, 2011. PMID 21912624, Free PMC Article
    2. Transcriptional Regulatory Networks Involved in C3-C4 Alcohol Stress Response and Tolerance in Yeast. Liang L, et al. ACS Synth Biol, 2021 Jan 15. PMID 33356165
    3. Global analysis of the yeast osmotic stress response by quantitative proteomics. Soufi B, et al. Mol Biosyst, 2009 Nov. PMID 19823750
    4. A systems approach to delineate functions of paralogous transcription factors: role of the Yap family in the DNA damage response. Tan K, et al. Proc Natl Acad Sci U S A, 2008 Feb 26. PMID 18287073, Free PMC Article
    5. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Fernandes L, et al. Mol Cell Biol, 1997 Dec. PMID 9372930, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Yap3p
    NP_011854.1
    • Basic leucine zipper (bZIP) transcription factor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      84068..85060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179089.1 → NP_011854.1  TPA: Yap3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011854.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKQ4, P38749
      UniProtKB/TrEMBL
      A0A8H4F9T2, G2WF58
      Conserved Domains (1) summary
      cd14688
      Location:145 → 207
      bZIP_YAP; Basic leucine zipper (bZIP) domain of Yeast Activator Protein (YAP) and similar proteins: a DNA-binding and dimerization domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38749.1

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