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    meu13 homologous-pairing protein 2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361533, updated on 22-Jun-2024

    Summary

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    Gene symbol
    meu13
    Gene description
    homologous-pairing protein 2
    Locus tag
    SPOM_SPAC222.15
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC821.01
    Old locus tag
    SPAC222.15
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    Genomic context

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    See meu13 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003424.3 (977709..978637)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene GTP-binding protein Sey1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Srp1 family splicing factor Neighboring gene ncRNA Neighboring gene COP9/signalosome complex subunit Csn3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel meiosis-specific protein of fission yeast, Meu13p, promotes homologous pairing independently of homologous recombination. Nabeshima K, et al. EMBO J, 2001 Jul 16. PMID 11447128, Free PMC Article
    2. Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases. Ploquin M, et al. Nucleic Acids Res, 2007. PMID 17426123, Free PMC Article
    3. Mcp7, a meiosis-specific coiled-coil protein of fission yeast, associates with Meu13 and is required for meiotic recombination. Saito TT, et al. Nucleic Acids Res, 2004. PMID 15210864, Free PMC Article
    4. Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast. Pérez-Hidalgo L, et al. J Cell Sci, 2003 Jan 15. PMID 12482912
    5. TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint. Perera D, et al. Mol Biol Cell, 2004 Apr. PMID 14718568, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables recombinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables recombinase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in homologous chromosome pairing at meiosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in homologous chromosome pairing at meiosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in meiotic joint molecule formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic joint molecule formation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in meiotic strand invasion involved in reciprocal meiotic recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in meiotic strand invasion involved in reciprocal meiotic recombination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA recombinase auxiliary factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of DNA recombinase auxiliary factor complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in condensed nuclear chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homologous-pairing protein 2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      977709..978637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018551.1 → NP_001018191.1  homologous-pairing protein 2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_001018191.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HGK2
      Conserved Domains (1) summary
      pfam07106
      Location:21 → 185
      TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
    Nucleotide Protein
    Heading Accession and Version

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