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    ppk32 serine/threonine protein kinase Ppk32 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541327, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ppk32
    Official Full Name
    serine/threonine protein kinase Ppk32
    Primary source
    PomBase:SPBP23A10.10
    Locus tag
    SPOM_SPBP23A10.10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ppk32 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (2016248..2018936)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ino80, NuA4 and Swr1 complex actin-like protein Arp4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GINS complex subunit Psf1 Neighboring gene circularly permuted 1,3-beta-glucanase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission Yeast SCYL1/2 Homologue Ppk32: A Novel Regulator of TOR Signalling That Governs Survival during Brefeldin A Induced Stress to Protein Trafficking. Kowalczyk KM, et al. PLoS Genet, 2016 May. PMID 27191590, Free PMC Article
    2. Systematic deletion analysis of fission yeast protein kinases. Bimbó A, et al. Eukaryot Cell, 2005 Apr. PMID 15821139, Free PMC Article
    3. TOR complex 2 localises to the cytokinetic actomyosin ring and controls the fidelity of cytokinesis. Baker K, et al. J Cell Sci, 2016 Jul 1. PMID 27206859, Free PMC Article
    4. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. n summary, Ppk32 reduce TOR signalling in response to BFA induced stress to support cell survival.
      Title: Fission Yeast SCYL1/2 Homologue Ppk32: A Novel Regulator of TOR Signalling That Governs Survival during Brefeldin A Induced Stress to Protein Trafficking.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of TORC1 signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine protein kinase Ppk32

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2016248..2018936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021726.3 → NP_595822.1  serine/threonine protein kinase Ppk32 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595822.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7X5
      Conserved Domains (3) summary
      cd14011
      Location:23 → 317
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      pfam00069
      Location:33 → 317
      Pkinase; Protein kinase domain
      sd00044
      Location:363 → 385
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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