U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    abp1 cofilin/tropomyosin family protein abp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542979, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    abp1
    Official Full Name
    cofilin/tropomyosin family protein abp1
    Primary source
    PomBase:SPAPJ760.02c
    Locus tag
    SPOM_SPAPJ760.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See abp1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (5261935..5265046, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F1-FO ATP synthase alpha subunit Neighboring gene dipeptidyl peptidase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein adg1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The fission yeast CENP-B protein Abp1 prevents pervasive transcription of repetitive DNA elements. Daulny A, et al. Biochim Biophys Acta, 2016 Oct. PMID 27345571, Free PMC Article
    2. Structure of the replication regulator Sap1 reveals functionally important interfaces. Jørgensen MM, et al. Sci Rep, 2018 Jul 19. PMID 30026545, Free PMC Article
    3. Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization. Murton HE, et al. Genetics, 2016 Aug. PMID 27343236, Free PMC Article
    4. Role of actin polymerization and actin cables in actin-patch movement in Schizosaccharomyces pombe. Pelham RJ Jr, et al. Nat Cell Biol, 2001 Mar. PMID 11231572
    5. A stable microtubule array drives fission yeast polarity reestablishment upon quiescence exit. Laporte D, et al. J Cell Biol, 2015 Jul 6. PMID 26124291, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The results suggest that Abp1 prevents pervasive RNAPII transcription of repetitive DNA elements (ie, Tf2 and rDNA repeats) from internal cryptic sites.
      Title: The fission yeast CENP-B protein Abp1 prevents pervasive transcription of repetitive DNA elements.
    2. we describe the impact of silencing and clustering on the mobility of an endogenous Tf2 element. Deletion of genes such as set1(+) or abp1(+) that both alleviate silencing and clustering, result in a corresponding increase in mobilization. Furthermore, expression of constitutively active Sre1, a transcriptional activator of Tf2 elements, also alleviates clustering and induces mobilization
      Title: Restriction of Retrotransposon Mobilization in Schizosaccharomyces pombe by Transcriptional Silencing and Higher-Order Chromatin Organization.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of actin filament polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in actin cortical patch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with actin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cortical actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in site of polarized growth IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    cofilin/tropomyosin family protein abp1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5261935..5265046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020353.3 → NP_594921.1  cofilin/tropomyosin family protein abp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594921.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78815, Q9P7E8
      Conserved Domains (3) summary
      cd11281
      Location:5 → 138
      ADF_drebrin_like; ADF homology domain of drebrin and actin-binding protein 1 (abp1)
      cd11961
      Location:804 → 856
      SH3_Abp1_fungi_C2; Second C-terminal Src homology 3 domain of Fungal Actin-binding protein 1
      cl17036
      Location:729 → 782
      SH3; Src Homology 3 domain superfamily
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials