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    YRB30 Yrb30p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852712, updated on 1-Aug-2024

    Summary

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    Gene symbol
    YRB30
    Gene description
    Yrb30p
    Primary source
    FungiDB:YGL164C
    Locus tag
    YGL164C
    See related
    SGD:S000003132; AllianceGenome:SGD:S000003132; VEuPathDB:YGL164C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables GTPase regulator activity. Predicted to be involved in protein transport and regulation of catalytic activity. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See YRB30 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (191978..193300, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Hur1p Neighboring gene Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 Neighboring gene Cup2p Neighboring gene DNA-dependent ATPase RAD54 Neighboring gene Sut1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae. Braunwarth A, et al. J Biol Chem, 2003 Apr 25. PMID 12578832
    2. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Willingham S, et al. Science, 2003 Dec 5. PMID 14657499
    3. Recruitment of Rpd3 to the telomere depends on the protein arginine methyltransferase Hmt1. Milliman EJ, et al. PLoS One, 2012. PMID 22953000, Free PMC Article
    4. Systems-level effects of allosteric perturbations to a model molecular switch. Perica T, et al. Nature, 2021 Nov. PMID 34646016, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. Tettelin H, et al. Nature, 1997 May 29. PMID 9169869

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Yrb30p
    NP_011351.1
    • RanGTP-binding protein; inhibits RanGAP1 (Rna1p)-mediated GTP hydrolysis of RanGTP (Gsp1p); shares similarity to proteins in other fungi but not in higher eukaryotes

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      191978..193300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181029.1 → NP_011351.1  TPA: Yrb30p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011351.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTY7, P53107, Q6LDS2
      UniProtKB/TrEMBL
      A6ZU21, B3LHL7, B5VIG2, C8Z887, N1P4C7
      Conserved Domains (1) summary
      pfam05508
      Location:1 → 310
      Ran-binding; RanGTP-binding protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53107.1

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