U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    win1 MAP kinase kinase kinase Win1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542988, updated on 22-Jun-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    win1
    Gene description
    MAP kinase kinase kinase Win1
    Locus tag
    SPOM_SPAC1006.09
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC1250.06c; SPAPJ730.01
    Old locus tag
    SPAC1006.09
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See win1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5089816..5094848)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Spg1-binding protein Etd1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 60S ribosomal protein eL30

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Azoles activate Atf1-mediated transcription through MAP kinase pathway for antifungal effects in fission yeast. Hu L, et al. Genes Cells, 2015 Sep. PMID 26108447
    2. Isolation of a novel type of mutation in the mitotic control of Schizosaccharomyces pombe whose phenotypic expression is dependent on the genetic background and nutritional environment. Ogden JE, et al. Curr Genet, 1986. PMID 3442828
    3. Response to arsenate treatment in Schizosaccharomyces pombe and the role of its arsenate reductase activity. Salgado A, et al. PLoS One, 2012. PMID 22912829, Free PMC Article
    4. Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe. Tatebe H, et al. Curr Biol, 2005 Jun 7. PMID 15936270
    5. The fission yeast mitotic regulator win1+ encodes an MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarity. Samejima I, et al. Mol Biol Cell, 1998 Aug. PMID 9693384, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate that Mcs4 is required for stable heteromer formation between the Wis4 and Win1 MAPKKKs.
      Title: Response regulator-mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables MAP kinase kinase kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in p38MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in p38MAPK cascade IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in p38MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Mcs4 RR-MAPKKK complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Mcs4 RR-MAPKKK complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    MAP kinase kinase kinase Win1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5089816..5094848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020285.3 → NP_594856.2  MAP kinase kinase kinase Win1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594856.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74304, Q9P7R1, Q9UTP1, Q9UTR3
      Conserved Domains (2) summary
      smart00220
      Location:1120 → 1406
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06626
      Location:1119 → 1406
      STKc_MEKK4; Catalytic domain of the Protein Serine/Threonine Kinase, Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 4
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials