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    GIS3 Gis3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850783, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GIS3
    Official Full Name
    Gis3p
    Primary source
    SGD:S000004084
    Locus tag
    YLR094C
    See related
    AllianceGenome:SGD:S000004084; FungiDB:YLR094C; VEuPathDB:YLR094C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in intracellular signal transduction. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See GIS3 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (327730..329238, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene sulfate permease Neighboring gene Nyv1p Neighboring gene Ioc2p Neighboring gene serine/threonine protein kinase KIN2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast. Araki T, et al. Genes Genet Syst, 2005 Oct. PMID 16394584
    2. Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells. Balciunas D, et al. Mol Gen Genet, 1999 Dec. PMID 10628841
    3. CROP: a retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system. Courtellemont T, et al. EMBO J, 2022 May 16. PMID 35466426, Free PMC Article
    4. Functional analysis of the Saccharomyces cerevisiae YFR021w/YGR223c/YPL100w ORF family suggests relations to mitochondrial/peroxisomal functions and amino acid signalling pathways. Georgakopoulos T, et al. Yeast, 2001 Sep 15. PMID 11536337
    5. Whi3, an S. cerevisiae RNA-binding protein, is a component of stress granules that regulates levels of its target mRNAs. Holmes KJ, et al. PLoS One, 2013. PMID 24386330, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Gis3p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      327730..329238 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181981.1 → NP_013195.1  TPA: Gis3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013195.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY94, Q12418, Q7LGX3
      UniProtKB/TrEMBL
      A7A0Z8, B3LT62, C7GQR7, C8ZD64, G2WIT7, N1NZK5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12418.1

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