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    SWC7 Swc7p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851101, updated on 29-Jun-2024

    Summary

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    Gene symbol
    SWC7
    Gene description
    Swc7p
    Primary source
    FungiDB:YLR385C
    Locus tag
    YLR385C
    See related
    SGD:S000004377; AllianceGenome:SGD:S000004377; VEuPathDB:YLR385C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    AWS1
    Summary
    Involved in chromatin remodeling. Located in nucleus. Part of Swr1 complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SWC7 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (892992..893390, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene DNA repair protein SMC6 Neighboring gene Elongator subunit IKI3 Neighboring gene Vac14p Neighboring gene Reh1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP binding facilitates target search of SWR1 chromatin remodeler by promoting one-dimensional diffusion on DNA. Carcamo CC, et al. Elife, 2022 Jul 25. PMID 35876491, Free PMC Article
    2. Functional characterization and architecture of recombinant yeast SWR1 histone exchange complex. Lin CL, et al. Nucleic Acids Res, 2017 Jul 7. PMID 28499038, Free PMC Article
    3. N terminus of Swr1 binds to histone H2AZ and provides a platform for subunit assembly in the chromatin remodeling complex. Wu WH, et al. J Biol Chem, 2009 Mar 6. PMID 19088068, Free PMC Article
    4. Bdf1 Bromodomains Are Essential for Meiosis and the Expression of Meiotic-Specific Genes. García-Oliver E, et al. PLoS Genet, 2017 Jan. PMID 28068333, Free PMC Article
    5. Dual function of Swc5 in SWR remodeling ATPase activation and histone H2A eviction. Sun L, et al. Nucleic Acids Res, 2017 Sep 29. PMID 28973436, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Swr1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Swc7p
    NP_013489.1
    • hypothetical protein; component of the Swr1p complex that incorporates Htz1p into chromatin

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      892992..893390 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182274.1 → NP_013489.1  TPA: Swc7p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013489.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ20, Q06707
      UniProtKB/TrEMBL
      A0A6A5PRC9, A7A1R0, N1NYR6
      Conserved Domains (1) summary
      pfam17330
      Location:26 → 128
      SWC7; SWR1 chromatin-remodelling complex, subunit Swc7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06707.1

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