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    bro1 vacuolar protein-sorting protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542419, updated on 18-Sep-2024

    Summary

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    Official Symbol
    bro1
    Official Full Name
    vacuolar protein-sorting protein
    Primary source
    PomBase:SPAC17G6.05c
    Locus tag
    SPOM_SPAC17G6.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See bro1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3596387..3598850, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene phosphoprotein phosphatase Neighboring gene protein farnesyltransferase beta subunit Cpp1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 40S ribosomal protein eS24 Neighboring gene SNARE protein Use1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TORC2 inhibition of α-arrestin Aly3 mediates cell surface persistence of S. pombe Ght5 glucose transporter in low glucose. Toyoda Y, et al. J Cell Sci, 2021 May 15. PMID 34028542
    2. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vacuolar protein-sorting protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3596387..3598850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019675.3 → NP_594252.1  vacuolar protein-sorting protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594252.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13783
      Conserved Domains (3) summary
      cd09237
      Location:382 → 745
      V_ScBro1_like; Protein-interacting V-domain of Saccharomyces cerevisiae Bro1 and related domains
      pfam13949
      Location:439 → 748
      ALIX_LYPXL_bnd; ALIX V-shaped domain binding to HIV
      cl14649
      Location:8 → 345
      BRO1_Alix_like; Protein-interacting Bro1-like domain of mammalian Alix and related domains
    Nucleotide Protein
    Heading Accession and Version

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