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    git7 SGT1-like protein Git7 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540962, updated on 18-Sep-2024

    Summary

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    Official Symbol
    git7
    Official Full Name
    SGT1-like protein Git7
    Primary source
    PomBase:SPBC36.12c
    Locus tag
    SPOM_SPBC36.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See git7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (864655..866029, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U2 snRNP-associated protein sap61 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene phosphatidic acid transfer protein Ups2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin hydrolase Ubp15 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation. Schadick K, et al. Eukaryot Cell, 2002 Aug. PMID 12456004, Free PMC Article
    2. Identification of an Hsp90 mutation that selectively disrupts cAMP/PKA signaling in Saccharomyces cerevisiae. Flom GA, et al. Curr Genet, 2012 Jun. PMID 22461145
    3. Six git genes encode a glucose-induced adenylate cyclase activation pathway in the fission yeast Schizosaccharomyces pombe. Byrne SM, et al. J Cell Sci, 1993 Aug. PMID 8227198, Free PMC Article
    4. Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway. Hoffman CS, et al. Genes Dev, 1991 Apr. PMID 1849107
    5. sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase. Jin M, et al. Genetics, 1995 Jun. PMID 7498728, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein-folding chaperone binding ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein folding IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SGT1-like protein Git7

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      864655..866029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021248.3 → NP_595340.1  SGT1-like protein Git7 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595340.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O59709, Q9C1X3
      Conserved Domains (3) summary
      cd06466
      Location:187 → 271
      p23_CS_SGT1_like; p23_like domain similar to the C-terminal CHORD-SGT1 (CS) domain of Sgt1 (suppressor of G2 allele of Skp1). Sgt1 interacts with multiple protein complexes and has the features of a cochaperone. Human (h) Sgt1 interacts with both Hsp70 and Hsp90, and has ...
      COG5091
      Location:1 → 379
      SGT1; Suppressor of G2 allele of skp1 and related proteins [General function prediction only]
      pfam05002
      Location:301 → 379
      SGS; SGS domain
    Nucleotide Protein
    Heading Accession and Version

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