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    fus1 formin Fus1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541741, updated on 18-Sep-2024

    Summary

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    Official Symbol
    fus1
    Official Full Name
    formin Fus1
    Primary source
    PomBase:SPAC20G4.02c
    Locus tag
    SPOM_SPAC20G4.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See fus1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4813111..4817786, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CCR4-Not complex subunit Caf16 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene eIF2 alpha kinase Hri1 Neighboring gene ncRNA Neighboring gene checkpoint clamp complex protein Hus1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FH3, a domain found in formins, targets the fission yeast formin Fus1 to the projection tip during conjugation. Petersen J, et al. J Cell Biol, 1998 Jun 1. PMID 9606213, Free PMC Article
    2. Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation. Petersen J, et al. Mol Cell Biol, 1995 Jul. PMID 7791776, Free PMC Article
    3. The Schizosaccharomyces pombe cfr1+ gene participates in mating through a new pathway that is independent of fus1+. Cartagena-Lirola H, et al. Yeast, 2006 Apr 15. PMID 16598689
    4. Tropomyosin is required for the cell fusion process during conjugation in fission yeast. Kurahashi H, et al. Genes Cells, 2002 Apr. PMID 11952834
    5. Ultrastructural plasma membrane asymmetries in tension and curvature promote yeast cell fusion. Muriel O, et al. J Cell Biol, 2021 Oct 4. PMID 34382996, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables SH3 domain binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytogamy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mating projection actin fusion focus assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in mating projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mating projection actin fusion focus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mating projection tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mating projection tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic actomyosin contractile ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    formin Fus1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4813111..4817786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020165.3 → NP_594737.1  formin Fus1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594737.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10719
      Conserved Domains (2) summary
      pfam02181
      Location:868 → 1253
      FH2; Formin Homology 2 Domain
      pfam06371
      Location:108 → 296
      Drf_GBD; Diaphanous GTPase-binding Domain
    Nucleotide Protein
    Heading Accession and Version

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