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    mot2 CCR4-Not complex subunit Mot2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542325, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mot2
    Official Full Name
    CCR4-Not complex subunit Mot2
    Primary source
    PomBase:SPAC16C9.04c
    Locus tag
    SPOM_SPAC16C9.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    not4
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    Genomic context

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    See mot2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (796876..798802, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene export adaptor Nmd3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Clr6 histone deacetylase-associated PHD protein-1 Cph1 Neighboring gene ATP-dependent RNA helicase Upf1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The architecture of the Schizosaccharomyces pombe CCR4-NOT complex. Ukleja M, et al. Nat Commun, 2016 Jan 25. PMID 26804377, Free PMC Article
    2. RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not. Webster MW, et al. Elife, 2019 Jan 2. PMID 30601114, Free PMC Article
    3. mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases. Webster MW, et al. Mol Cell, 2018 Jun 21. PMID 29932902, Free PMC Article
    4. Ubiquitination-dependent control of sexual differentiation in fission yeast. Simonetti F, et al. Elife, 2017 Aug 25. PMID 28841135, Free PMC Article
    5. Enhancer of Rudimentary Cooperates with Conserved RNA-Processing Factors to Promote Meiotic mRNA Decay and Facultative Heterochromatin Assembly. Sugiyama T, et al. Mol Cell, 2016 Mar 3. PMID 26942678, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulatory ncRNA-mediated gene silencing EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCR4-NOT complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of CCR4-NOT complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of CCR4-NOT core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    CCR4-Not complex subunit Mot2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      796876..798802 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018475.3 → NP_593078.1  CCR4-Not complex subunit Mot2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593078.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09818
      Conserved Domains (3) summary
      COG5175
      Location:1 → 489
      MOT2; Transcriptional repressor [Transcription]
      cd12438
      Location:111 → 210
      RRM_CNOT4; RNA recognition motif in Eukaryotic CCR4-NOT transcription complex subunit 4 (NOT4) and similar proteins
      pfam14570
      Location:18 → 64
      zf-RING_4; RING/Ubox like zinc-binding domain
    Nucleotide Protein
    Heading Accession and Version

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