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    erf1 cytoplasmic translation release factor class I eRF1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542148, updated on 18-Sep-2024

    Summary

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    Official Symbol
    erf1
    Official Full Name
    cytoplasmic translation release factor class I eRF1
    Primary source
    PomBase:SPAC1834.01
    Locus tag
    SPOM_SPAC1834.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    sup45
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    Genomic context

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    See erf1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4691780..4693738)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase Neighboring gene sister chromatid cohesion protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GDP-mannose transporter Vrg4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene multifunctional aromatic polypeptide Aro1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe. Kong C, et al. Mol Cell, 2004 Apr 23. PMID 15099522
    2. The stretch of C-terminal acidic amino acids of translational release factor eRF1 is a primary binding site for eRF3 of fission yeast. Ito K, et al. RNA, 1998 Aug. PMID 9701287, Free PMC Article
    3. Structure of the Dom34-Hbs1 complex and implications for no-go decay. Chen L, et al. Nat Struct Mol Biol, 2010 Oct. PMID 20890290
    4. C-terminal interaction of translational release factors eRF1 and eRF3 of fission yeast: G-domain uncoupled binding and the role of conserved amino acids. Ebihara K, et al. RNA, 1999 Jun. PMID 10376874, Free PMC Article
    5. Structural insights into eRF3 and stop codon recognition by eRF1. Cheng Z, et al. Genes Dev, 2009 May 1. PMID 19417105, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTPase regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific mRNA binding EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables sequence-specific mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to translation release factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables translation release factor activity, codon specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translational termination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translational termination IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of translation release factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of translation release factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of translation release factor complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of translation release factor complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytoplasmic translation release factor class I eRF1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4691780..4693738
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020109.3 → NP_594680.1  cytoplasmic translation release factor class I eRF1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594680.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P79063
      Conserved Domains (4) summary
      COG1503
      Location:1 → 418
      eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]
      pfam03463
      Location:15 → 136
      eRF1_1; eRF1 domain 1
      pfam03464
      Location:143 → 274
      eRF1_2; eRF1 domain 2
      pfam03465
      Location:277 → 416
      eRF1_3; eRF1 domain 3
    Nucleotide Protein
    Heading Accession and Version

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