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    prp31 U4/U6 x U5 tri-snRNP complex subunit Prp31 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540045, updated on 18-Sep-2024

    Summary

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    Official Symbol
    prp31
    Official Full Name
    U4/U6 x U5 tri-snRNP complex subunit Prp31
    Primary source
    PomBase:SPBC119.13c
    Locus tag
    SPOM_SPBC119.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See prp31 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (741836..743843, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene golgin protein Rud3 Neighboring gene ncRNA Neighboring gene tRNA-Ser Neighboring gene protein Mdm35

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation of an essential Schizosaccharomyces pombe gene, prp31(+), that links splicing and meiosis. Bishop DT, et al. Nucleic Acids Res, 2000 Jun 1. PMID 10871341, Free PMC Article
    2. Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe. Bottner CA, et al. Curr Genet, 2005 Sep. PMID 16133344
    3. The N-terminus of Prp1 (Prp6/U5-102 K) is essential for spliceosome activation in vivo. Lützelberger M, et al. Nucleic Acids Res, 2010 Mar. PMID 20007600, Free PMC Article
    4. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article
    5. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Carnahan RH, et al. Eukaryot Cell, 2005 Mar. PMID 15755920, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mRNA cis splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spliceosomal tri-snRNP complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    U4/U6 x U5 tri-snRNP complex subunit Prp31

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      741836..743843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021201.3 → NP_595294.1  U4/U6 x U5 tri-snRNP complex subunit Prp31 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595294.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42904
      Conserved Domains (3) summary
      smart00931
      Location:120 → 171
      NOSIC; NOSIC (NUC001) domain
      COG1498
      Location:1 → 400
      SIK1; RNA processing factor Prp31, contains Nop domain [Translation, ribosomal structure and biogenesis]
      pfam09785
      Location:361 → 483
      Prp31_C; Prp31 C terminal domain
    Nucleotide Protein
    Heading Accession and Version

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