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    PES4 Pes4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850579, updated on 18-Sep-2024

    Summary

    Official Symbol
    PES4
    Official Full Name
    Pes4p
    Primary source
    SGD:S000001919
    Locus tag
    YFR023W
    See related
    AllianceGenome:SGD:S000001919; FungiDB:YFR023W; VEuPathDB:YFR023W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Involved in mRNA localization resulting in posttranscriptional regulation of gene expression; mRNA metabolic process; and regulation of translation. Located in prospore membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See PES4 in Genome Data Viewer
    Location:
    chromosome: VI
    Exon count:
    1
    Sequence:
    Chromosome: VI; NC_001138.5 (199874..201709)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene Rog3p Neighboring gene ncRNA Neighboring gene Lsb3p Neighboring gene histidinol-phosphatase

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables poly(A) binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables poly(U) RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA localization resulting in post-transcriptional regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mRNA metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of translation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in sporulation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasmic stress granule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Pes4p
    NP_116678.1
    • Putative RNA binding protein; partially redundant function with paralog MIP6 in the steady-state expression, translational timing and localization of a subset of Ndt80-dependent mRNAs that are protected until translated near the end of meiosis II; regulator of meiotic commitment; redundant function with MIP6 in sporulation; localizes to puncta near the openings of the prospore membrane; suppressor of a DNA polymerase epsilon mutation; induced by NDT80

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      199874..201709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179988.1NP_116678.1  TPA: Pes4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_116678.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTQ3, P39684
      UniProtKB/TrEMBL
      A7A260, B3LUN2, B5VI50, C7GYC8, C8Z7V8, N1P4Q2
      Conserved Domains (1) summary
      TIGR01628
      Location:93461
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family