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    btb3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542872, updated on 11-Sep-2024

    Summary

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    Official Symbol
    btb3
    Primary source
    PomBase:SPAC13D6.04c
    Locus tag
    SPOM_SPAC13D6.04C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (2251442..2253352, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA (uridine) methyltransferase trm9 Neighboring gene ncRNA Neighboring gene tubulin-specific chaperone cofactor B Neighboring gene ncRNA Neighboring gene ribonuclease H2 complex subunit Rnh201

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferase. Maezawa S, et al. Genes Cells, 2008 May. PMID 18429817
    2. BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Geyer R, et al. Mol Cell, 2003 Sep. PMID 14527422
    3. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ubiquitin ligase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin ligase Btb3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2251442..2253352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019114.3 → NP_593682.1  ubiquitin ligase Btb3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593682.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10225
      Conserved Domains (5) summary
      smart00225
      Location:168 → 262
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cd00204
      Location:56 → 139
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam00651
      Location:164 → 256
      BTB; BTB/POZ domain
      pfam12796
      Location:56 → 140
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:56 → 83
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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