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    blt1 ubiquitin domain-like protein Blt1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540380, updated on 18-Sep-2024

    Summary

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    Official Symbol
    blt1
    Official Full Name
    ubiquitin domain-like protein Blt1
    Primary source
    PomBase:SPBC1A4.05
    Locus tag
    SPOM_SPBC1A4.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See blt1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (1984466..1988552)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative protein Tam41 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U3 snoRNP-associated protein Sof1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A unique kinesin-like protein, Klp8, is involved in mitosis and cell morphology through microtubule stabilization. Kashiwazaki J, et al. Cytoskeleton (Hoboken), 2019 May. PMID 31276301
    2. Fission yeast type 2 node proteins Blt1p and Gef2p cooperate to ensure timely completion of cytokinesis. Kwon L, et al. BMC Mol Cell Biol, 2019 Jan 24. PMID 31041892, Free PMC Article
    3. Blt1 and Mid1 provide overlapping membrane anchors to position the division plane in fission yeast. Guzman-Vendrell M, et al. Mol Cell Biol, 2013 Jan. PMID 23149940, Free PMC Article
    4. Septins regulate the equatorial dynamics of the separation initiation network kinase Sid2p and glucan synthases to ensure proper cytokinesis. Zheng S, et al. FEBS J, 2018 Jul. PMID 29722930
    5. Anillin-related protein Mid1p coordinates the assembly of the cytokinetic contractile ring in fission yeast. Saha S, et al. Mol Biol Cell, 2012 Oct. PMID 22918943, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Blt1p and Gef2p work in the same pathway, rather than in parallel, to localize the NDR-family kinase Sid2p and its regulatory partner Mob1p to the division site, thereby promoting timely completion of cell division.
      Title: Fission yeast type 2 node proteins Blt1p and Gef2p cooperate to ensure timely completion of cytokinesis.
    2. Blt1p ensures proper timing for onset of contractile ring constriction during cytokinesis.
      Title: Characterization of the roles of Blt1p in fission yeast cytokinesis.
    3. Blt1 acts as a scaffolding protein for precursors of the cytokinetic ring, and Blt1 and Mid1 provide overlapping membrane anchors for proper division plane positioning.
      Title: Blt1 and Mid1 provide overlapping membrane anchors to position the division plane in fission yeast.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables cytoskeletal protein-membrane anchor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in medial cortical node IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic actomyosin contractile ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic actomyosin contractile ring, intermediate layer IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin domain-like protein Blt1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1984466..1988552
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356242.2 → NP_001342740.1  ubiquitin domain-like protein Blt1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74338
      Conserved Domains (2) summary
      PHA01816
      Location:58 → 144
      PHA01816; hypothetical protein
      cl25732
      Location:338 → 578
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein
    Heading Accession and Version

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