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    PEX9 Pex9p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855032, updated on 29-Jun-2024

    Summary

    Gene symbol
    PEX9
    Gene description
    Pex9p
    Primary source
    FungiDB:YMR018W
    Locus tag
    YMR018W
    See related
    SGD:S000004620; AllianceGenome:SGD:S000004620; VEuPathDB:YMR018W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable peroxisome matrix targeting signal-1 binding activity. Involved in protein import into peroxisome matrix. Located in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See PEX9 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (310208..311752)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Sok2p Neighboring gene Spo20p Neighboring gene Stb4p Neighboring gene polyamine oxidase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables peroxisome matrix targeting signal-1 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peroxisome matrix targeting signal-1 binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein import into peroxisome matrix IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in protein import into peroxisome matrix IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein import into peroxisome matrix IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    involved_in protein import into peroxisome matrix, docking IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisomal membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Pex9p
    NP_013731.1
    • Peroxisomal membrane signal receptor for peroxisomal matrix proteins; oleate-inducible condition-specific import receptor for a subset of PTS1-containing matrix proteins; localizes to both the cytosol and the peroxisomal membrane; similar to human PEX5Rp, a peroxin protein 5 related protein; paralog of Pex5p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      310208..311752
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182514.1NP_013731.1  TPA: Pex9p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013731.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZJ2, Q04364, Q6B2L0
      UniProtKB/TrEMBL
      A0A8H4F7Z6, B3LLS0, B5VPE5, C7GLA1, C8ZEM6, G2WK69, N1NY68
      Conserved Domains (2) summary
      TIGR02917
      Location:234455
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:360388
      TPR; TPR repeat [structural motif]