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    hub1 ubiquitin-like protein modifier Hub1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540389, updated on 22-Jun-2024

    Summary

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    Gene symbol
    hub1
    Gene description
    ubiquitin-like protein modifier Hub1
    Locus tag
    SPOM_SPBC31E1.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ubl4
    Old locus tag
    SPBC31E1.03
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    Genomic context

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    See hub1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (243966..244982, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene autophagy-associated protein Atg2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene P-type calcium transport ATPase Pmr1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SNARE Pep12 Neighboring gene nucleoporin Gle1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hub1 is an essential ubiquitin-like protein without functioning as a typical modifier in fission yeast. Yashiroda H, et al. Genes Cells, 2004 Dec. PMID 15569151
    2. Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast. Wilkinson CR, et al. Curr Biol, 2004 Dec 29. PMID 15620657
    3. Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Mishra SK, et al. Nature, 2011 May 25. PMID 21614000, Free PMC Article
    4. Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. Thakran P, et al. EMBO J, 2018 Jan 4. PMID 28947618, Free PMC Article
    5. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tag activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein modification process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin-like protein modifier Hub1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      243966..244982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021006.3 → NP_595099.1  ubiquitin-like protein modifier Hub1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595099.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94650
      Conserved Domains (1) summary
      cd01791
      Location:1 → 73
      Ubl5; UBL5 ubiquitin-like modifier
    Nucleotide Protein
    Heading Accession and Version

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