U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rpb7 DNA-directed RNA polymerase complex II subunit Rpb7 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542097, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rpb7
    Official Full Name
    DNA-directed RNA polymerase complex II subunit Rpb7
    Primary source
    PomBase:SPACUNK4.06c
    Locus tag
    SPOM_SPACUNK4.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    csp3; SPAPYUK71.02
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rpb7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2902084..2903133)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene P-type calcium transport ATPase Cta4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tricalbin Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome-wide transcriptional response to altered levels of the Rpb7 subunit of RNA polymerase II identifies its role in DNA damage response in Schizosaccharomyces pombe. Kumar D, et al. FEMS Yeast Res, 2019 Jan 1. PMID 30395243
    2. Modulating the level of the Rpb7 subunit of RNA polymerase II affects cell separation in Schizosaccharomyces pombe. Kumar D, et al. Res Microbiol, 2015 Jan. PMID 25530312
    3. Rpb7 subunit of RNA polymerase II interacts with an RNA-binding protein involved in processing of transcripts. Mitsuzawa H, et al. Nucleic Acids Res, 2003 Aug 15. PMID 12907709, Free PMC Article
    4. RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe. Montes M, et al. FEBS J, 2017 Feb. PMID 28060464
    5. The Rpb4 subunit of fission yeast Schizosaccharomyces pombe RNA polymerase II is essential for cell viability and similar in structure to the corresponding subunits of higher eukaryotes. Sakurai H, et al. Mol Cell Biol, 1999 Nov. PMID 10523639, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In summary, results of whole-genome level gene expression analysis, as well as phenotypic and genetic experiments suggest a role for Rpb7 in DNA damage response in Schizosaccharomyces pombe.
      Title: Genome-wide transcriptional response to altered levels of the Rpb7 subunit of RNA polymerase II identifies its role in DNA damage response in Schizosaccharomyces pombe.
    2. RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression.
      Title: RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe.
    3. the most prominent phenotype of cells expressing reduced rpb7(+) is a defect in cell separation; findings also revealed that the transcription of specific cell septation genes was significantly reduced in these cells
      Title: Modulating the level of the Rpb7 subunit of RNA polymerase II affects cell separation in Schizosaccharomyces pombe.
    4. Rpb7 promotes pre-siRNA transcription required for RNAi-directed chromatin silencing.
      Title: RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation initiation factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in nuclear-transcribed mRNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of septum digestion after cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase II, core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase II, core complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase II, holoenzyme EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-directed RNA polymerase complex II subunit Rpb7

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2902084..2903133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356091.2 → NP_001342741.1  DNA-directed RNA polymerase complex II subunit Rpb7 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14459
      Conserved Domains (1) summary
      COG1095
      Location:2 → 172
      RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials