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    isp7 2-oxoglutarate-Fe(2+) oxygenase superfamily protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542728, updated on 18-Sep-2024

    Summary

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    Official Symbol
    isp7
    Official Full Name
    2-oxoglutarate-Fe(2+) oxygenase superfamily protein
    Primary source
    PomBase:SPAC25B8.13c
    Locus tag
    SPOM_SPAC25B8.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See isp7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4179961..4183019, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene nucleotide-sugar phosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 5S ribosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway. Laor D, et al. Mol Cell Biol, 2014 Mar. PMID 24344203, Free PMC Article
    2. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    3. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of isp7(+) induces TORC1-dependent phosphorylation.
      Title: Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 2-oxoglutarate-dependent dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    2-oxoglutarate-Fe(2+) oxygenase superfamily protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4179961..4183019 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019902.3 → NP_594473.1  2-oxoglutarate-Fe(2+) oxygenase superfamily protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594473.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P40902
      Conserved Domains (3) summary
      COG3491
      Location:20 → 397
      PcbC; Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism]
      pfam03171
      Location:264 → 352
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
      pfam14226
      Location:26 → 111
      DIOX_N; non-haem dioxygenase in morphine synthesis N-terminal
    Nucleotide Protein
    Heading Accession and Version

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