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    hom3 aspartate kinase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540602, updated on 22-Jun-2024

    Summary

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    Gene symbol
    hom3
    Gene description
    aspartate kinase
    Locus tag
    SPOM_SPBC19F5.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPBC19F5.04
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    Genomic context

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    See hom3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (3709246..3711433)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene U3 snoRNP protein Utp4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene inositol polyphosphate phosphatase Neighboring gene ncRNA Neighboring gene pescadillo-family ribosome biogenesis protein Neighboring gene ncRNA Neighboring gene nucleolar protein Dnt1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    2. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
    3. Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. Heo DH, et al. Cell Rep, 2021 Sep 7. PMID 34496258, Free PMC Article
    4. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
    5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aspartate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in asparagine catabolic process NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in aspartate metabolic process IC
    Inferred by Curator
    more info
    		  
    involved_in homoserine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lysine biosynthetic process via diaminopimelate IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in methionine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in threonine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    aspartate kinase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3709246..3711433
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022463.3 → NP_596542.1  aspartate kinase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596542.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60163
      Conserved Domains (4) summary
      cd04919
      Location:431 → 496
      ACT_AK-Hom3_2; ACT domains located C-terminal to the catalytic domain of the aspartokinase (AK) HOM3
      cd04934
      Location:358 → 429
      ACT_AK-Hom3_1; CT domains located C-terminal to the catalytic domain of the aspartokinase (AK) HOM3, a monofunctional class enzyme found in Saccharomyces cerevisiae, and other related ACT domains
      COG0527
      Location:15 → 496
      LysC; Aspartokinase [Amino acid transport and metabolism]
      cd04247
      Location:14 → 319
      AAK_AK-Hom3; AAK_AK-Hom3: Amino Acid Kinase Superfamily (AAK), AK-Hom3; this CD includes the N-terminal catalytic domain of the aspartokinase HOM3, a monofunctional class enzyme found in Saccharomyces cerevisiae and other related AK domains. Aspartokinase, the first ...
    Nucleotide Protein
    Heading Accession and Version

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