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    mcp6 horsetail movement protein Hrs1/Mcp6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541097, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mcp6
    Official Full Name
    horsetail movement protein Hrs1/Mcp6
    Primary source
    PomBase:SPBC582.06c
    Locus tag
    SPOM_SPBC582.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    hrs1; mug3
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    Genomic context

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    See mcp6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (429183..430166, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene BRCT domain protein Brc1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 19S proteasome regulatory subunit Rpn7 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mcp6, a meiosis-specific coiled-coil protein of Schizosaccharomyces pombe, localizes to the spindle pole body and is required for horsetail movement and recombination. Saito TT, et al. J Cell Sci, 2005 Jan 15. PMID 15654021
    2. Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation. Fennell A, et al. J Cell Biol, 2015 Feb 16. PMID 25688135, Free PMC Article
    3. Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement. Tanaka K, et al. Curr Biol, 2005 Aug 23. PMID 16111942
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Hrs1p/Mcp6p on the meiotic spindle pole body organizes astral microtubule arrays for oscillatory nuclear movement.
      Title: Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement.
    2. Mcp6 (meiotic coiled-coil protein 6), which is a meiosis-specific, coiled-coil protein that localizes to the spindle-pole body (SPB), controls horsetail movement by regulating the astral microtubule organization during meiosis. [mcp6]
      Title: Mcp6, a meiosis-specific coiled-coil protein of Schizosaccharomyces pombe, localizes to the spindle pole body and is required for horsetail movement and recombination.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dynein-driven meiotic oscillatory nuclear movement IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in homologous chromosome pairing at meiosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in horsetail-astral microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in meiotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    horsetail movement protein Hrs1/Mcp6

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      429183..430166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021082.1 → NP_595174.1  horsetail movement protein Hrs1/Mcp6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595174.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10336
      Conserved Domains (1) summary
      COG1196
      Location:62 → 261
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version

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