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    rho5 Rho family GTPase Rho5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542013, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rho5
    Official Full Name
    Rho family GTPase Rho5
    Primary source
    PomBase:SPAC20H4.11c
    Locus tag
    SPOM_SPAC20H4.11C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rho5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2131685..2133051, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase E4 Neighboring gene family protein ICE2 Neighboring gene ncRNA Neighboring gene 40S ribosomal protein uS12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast Rho5p GTPase is a functional paralogue of Rho1p that plays a role in survival of spores and stationary-phase cells. Rincón SA, et al. Eukaryot Cell, 2006 Mar. PMID 16524899, Free PMC Article
    2. Small GTPase Rho5 is a functional homologue of Rho1, which controls cell shape and septation in fission yeast. Nakano K, et al. FEBS Lett, 2005 Sep 26. PMID 16146630
    3. Geranylgeranyltransferase Cwg2-Rho4/Rho5 module is implicated in the Pmk1 MAP kinase-mediated cell wall integrity pathway in fission yeast. Doi A, et al. Genes Cells, 2015 Apr. PMID 25651781
    4. Role of guanine nucleotide exchange factors for Rho family GTPases in the regulation of cell morphology and actin cytoskeleton in fission yeast. Iwaki N, et al. Biochem Biophys Res Commun, 2003 Dec 12. PMID 14637153
    5. Cooperation between Rho-GEF Gef2 and its binding partner Nod1 in the regulation of fission yeast cytokinesis. Zhu YH, et al. Mol Biol Cell, 2013 Oct. PMID 23966468, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rho4 and Rho5 deletion cells exhibited the vic phenotype and cell wall integrity defects, shared phenotypes among the components of the Pmk1 MAPK pathway.
      Title: Geranylgeranyltransferase Cwg2-Rho4/Rho5 module is implicated in the Pmk1 MAP kinase-mediated cell wall integrity pathway in fission yeast.
    2. Results suggest that the small GTPase Rho5 has an overlapping function with the small GTPase Rho1 in controlling cell growth and division.
      Title: Small GTPase Rho5 is a functional homologue of Rho1, which controls cell shape and septation in fission yeast.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of endocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of fungal-type cell wall biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane of cell tip IC
    Inferred by Curator
    more info
    		  

    General protein information

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    Preferred Names
    Rho family GTPase Rho5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2131685..2133051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019062.3 → NP_593631.1  Rho family GTPase Rho5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593631.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HE04
      Conserved Domains (2) summary
      smart00174
      Location:9 → 182
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
      cd01870
      Location:6 → 180
      RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC
    Nucleotide Protein
    Heading Accession and Version

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