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    ATP22 Atp22p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851952, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATP22
    Official Full Name
    Atp22p
    Primary source
    SGD:S000002758
    Locus tag
    YDR350C
    See related
    AllianceGenome:SGD:S000002758; FungiDB:YDR350C; VEuPathDB:YDR350C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    TCM10
    Summary
    Enables translation regulator activity. Involved in positive regulation of mitochondrial translation and proton-transporting two-sector ATPase complex assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ATP22 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1176120..1178174, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene putative aspartic endopeptidase Neighboring gene tRNA-Met Neighboring gene Sbe2p Neighboring gene Ypq2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. [Accumulation of inorganic polyphosphates of different fractions in mutant Saccharomyces cerevisiae with an error in synthesis ATP of mitochondria]. Tomashevskiĭ AA, et al. Mikrobiologiia, 2010 Jan-Feb. PMID 20411658
    2. ATP22, a nuclear gene required for expression of the F0 sector of mitochondrial ATPase in Saccharomyces cerevisiae. Helfenbein KG, et al. J Biol Chem, 2003 May 30. PMID 12646576
    3. The Saccharomyces cerevisiae ATP22 gene codes for the mitochondrial ATPase subunit 6-specific translation factor. Zeng X, et al. Genetics, 2007 Jan. PMID 17110482, Free PMC Article
    4. F1-dependent translation of mitochondrially encoded Atp6p and Atp8p subunits of yeast ATP synthase. Rak M, et al. Proc Natl Acad Sci U S A, 2009 Nov 3. PMID 19841266, Free PMC Article
    5. Spatial orchestration of mitochondrial translation and OXPHOS complex assembly. Stoldt S, et al. Nat Cell Biol, 2018 May. PMID 29662179

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mitochondrial ATP synthase of Saccharomyces cerevisiae plays role in accumulation of inorganic polyphosphates during fungus growth on culture media with glucose.
      Title: [Accumulation of inorganic polyphosphates of different fractions in mutant Saccharomyces cerevisiae with an error in synthesis ATP of mitochondria].
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation regulator activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables translation regulator activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of mitochondrial translation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of mitochondrial translation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton-transporting two-sector ATPase complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Atp22p
    NP_010637.4
    • Specific translational activator for the mitochondrial ATP6 mRNA; Atp6p encodes a subunit of F1F0 ATP synthase; localized to the mitochondrial inner membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1176120..1178174 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180658.4 → NP_010637.4  TPA: Atp22p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010637.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZYV0, B5VGN1, C8Z5R1, D6VSY0, P50273
      UniProtKB/TrEMBL
      N1P700
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P50273.1

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