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    RPS19B ribosomal 40S subunit protein S19B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855414, updated on 3-Nov-2024

    Summary

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    Official Symbol
    RPS19B
    Official Full Name
    ribosomal 40S subunit protein S19B
    Primary source
    SGD:S000005246
    Locus tag
    YNL302C
    See related
    AllianceGenome:SGD:S000005246; FungiDB:YNL302C; VEuPathDB:YNL302C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RP55B
    Summary
    A structural constituent of ribosome. Involved in ribosomal small subunit biogenesis and ribosomal subunit export from nucleus. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia and Diamond-Blackfan anemia 1. Orthologous to human RPS19 (ribosomal protein S19). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See RPS19B in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    2
    Sequence:
    Chromosome: XIV; NC_001146.8 (61958..62943, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Bxi1p Neighboring gene Rab family GTPase YPT11 Neighboring gene ribosomal 60S subunit protein L18B Neighboring gene Tos6p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of promoter elements of a ribosomal protein gene in Saccharomyces cerevisiae under various physiological conditions. Papciak SM, et al. Mol Gen Genet, 1992 Jul. PMID 1495481
    2. Genetic evidence for 18S rRNA binding and an Rps19p assembly function of yeast nucleolar protein Nep1p. Buchhaupt M, et al. Mol Genet Genomics, 2006 Sep. PMID 16721597
    3. Genetic mapping of two pairs of linked ribosomal protein genes in Saccharomyces cerevisiae. Papciak SM, et al. Curr Genet, 1987. PMID 3329973
    4. Molecular basis of Diamond-Blackfan anemia: structure and function analysis of RPS19. Gregory LA, et al. Nucleic Acids Res, 2007. PMID 17726054, Free PMC Article
    5. Association of RAP1 binding sites with stringent control of ribosomal protein gene transcription in Saccharomyces cerevisiae. Moehle CM, et al. Mol Cell Biol, 1991 May. PMID 2017175, Free PMC Article

    See all (84) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit biogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosomal small subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosomal subunit export from nucleus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in ribosomal subunit export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S19B
    NP_014097.1
    • Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19B has a paralog, RPS19A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      61958..62943 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183140.1 → NP_014097.1  TPA: ribosomal 40S subunit protein S19B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014097.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0P2, P07281
      UniProtKB/TrEMBL
      A6ZSH7, D3UFA5, G2WLG6, N1NY24
      Conserved Domains (1) summary
      pfam01090
      Location:5 → 142
      Ribosomal_S19e; Ribosomal protein S19e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P07281.2

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