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    shf1 histone H2B-K119 ubiquitin ligase complex (HULC) subunit Shf1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541675, updated on 18-Sep-2024

    Summary

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    Official Symbol
    shf1
    Official Full Name
    histone H2B-K119 ubiquitin ligase complex (HULC) subunit Shf1
    Primary source
    PomBase:SPAC22F8.12c
    Locus tag
    SPOM_SPAC22F8.12C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See shf1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4807981..4811408, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene putative U2 snRNP-associated protein Sap145 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphoinositide phospholipase C Plc1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CCR4-Not complex subunit Caf16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HULC, a histone H2B ubiquitinating complex, modulates heterochromatin independent of histone methylation in fission yeast. Zofall M, et al. J Biol Chem, 2007 May 11. PMID 17363370
    2. Histone H2B ubiquitination promotes the function of the anaphase-promoting complex/cyclosome in Schizosaccharomyces pombe. Elmore ZC, et al. G3 (Bethesda), 2014 Jun 19. PMID 24948786, Free PMC Article
    3. Promoter nucleosome dynamics regulated by signalling through the CTD code. Materne P, et al. Elife, 2015 Jun 22. PMID 26098123, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in epigenetic regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transcription elongation-coupled chromatin remodeling TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of HULC complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    histone H2B-K119 ubiquitin ligase complex (HULC) subunit Shf1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4807981..4811408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020163.3 → NP_594735.1  histone H2B-K119 ubiquitin ligase complex (HULC) subunit Shf1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594735.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UUI2
    Nucleotide Protein
    Heading Accession and Version

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