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    mam1 M-factor transmembrane transporter Mam1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540405, updated on 22-Jun-2024

    Summary

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    Gene symbol
    mam1
    Gene description
    M-factor transmembrane transporter Mam1
    Locus tag
    SPOM_SPBC25B2.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC2G5.09c
    Old locus tag
    SPBC25B2.02c
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    Genomic context

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    See mam1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2596405..2600486, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translation release factor complex GTPase subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene zf-C3HC4 type zinc finger Neighboring gene GTPase Mtg1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alternative protein secretion: the Mam1 ABC transporter supports secretion of M-factor linked GFP in fission yeast. Kjaerulff S, et al. Biochem Biophys Res Commun, 2005 Dec 30. PMID 16288715
    2. The Schizosaccharomyces pombe mam1 gene encodes an ABC transporter mediating secretion of M-factor. Christensen PU, et al. Mol Gen Genet, 1997 Jun. PMID 9236781
    3. Local Pheromone Release from Dynamic Polarity Sites Underlies Cell-Cell Pairing during Yeast Mating. Merlini L, et al. Curr Biol, 2016 Apr 25. PMID 27020743, Free PMC Article
    4. Spatial focalization of pheromone/MAPK signaling triggers commitment to cell-cell fusion. Dudin O, et al. Genes Dev, 2016 Oct 1. PMID 27798845, Free PMC Article
    5. A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant. Iwaki T, et al. Microbiology (Reading), 2006 Aug. PMID 16849797

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ABC-type oligopeptide transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peptide pheromone export by transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cortical dynamic polarity patch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    M-factor transmembrane transporter Mam1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2596405..2600486 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021982.4 → NP_001018819.2  M-factor transmembrane transporter Mam1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_001018819.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78966
      Conserved Domains (4) summary
      cd03228
      Location:434 → 645
      ABCC_MRP_Like; ATP-binding cassette domain of multidrug resistance protein-like transporters
      COG1132
      Location:767 → 1328
      MdlB; ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]
      cl00549
      Location:108 → 372
      ABC_membrane; ABC transporter transmembrane region
      cl21455
      Location:1099 → 1332
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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