U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mis6 centromere connector protein mis6 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542304, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mis6
    Official Full Name
    centromere connector protein mis6
    Primary source
    PomBase:SPAC1687.20c
    Locus tag
    SPOM_SPAC1687.20C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mis6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (939770..941944, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cohesin loading factor Ssl3 Neighboring gene ncRNA Neighboring gene queuine tRNA-ribosyltransferase Neighboring gene fructose-2,6-bisphosphatase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pumilio family RNA-binding protein Puf3

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Mis6, a fission yeast inner centromere protein, acts during G1/S and forms specialized chromatin required for equal segregation. Saitoh S, et al. Cell, 1997 Jul 11. PMID 9230309
    2. Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast. Takahashi K, et al. Science, 2000 Jun 23. PMID 10864871
    3. The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres. Walfridsson J, et al. Nucleic Acids Res, 2005. PMID 15908586, Free PMC Article
    4. Distinct protein interaction domains and protein spreading in a complex centromere. Partridge JF, et al. Genes Dev, 2000 Apr 1. PMID 10766735, Free PMC Article
    5. Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation. Goshima G, et al. Genes Dev, 1999 Jul 1. PMID 10398680, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CENP-A containing chromatin assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in CENP-A containing chromatin assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic sister chromatid segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Mis6-Sim4 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, centromeric core domain IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of inner kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of inner kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IC
    Inferred by Curator
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    centromere connector protein mis6

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      939770..941944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018535.2 → NP_593139.1  centromere connector protein mis6 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593139.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P87227
      Conserved Domains (1) summary
      pfam07778
      Location:12 → 337
      CENP-I; Mis6
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials