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    pmc4 mediator complex subunit Med4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539994, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pmc4
    Official Full Name
    mediator complex subunit Med4
    Primary source
    PomBase:SPBC1105.06
    Locus tag
    SPOM_SPBC1105.06
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    med4
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    Genomic context

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    See pmc4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3517461..3519089)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cell wall glucan 1,6-beta-glucosidase Exg1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene TREX/TREX2 complex subunit Pci2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene EMP70 family endosomal transport protein Emp70

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cdk11-cyclinL controls the assembly of the RNA polymerase II mediator complex. Drogat J, et al. Cell Rep, 2012 Nov 29. PMID 23122962
    2. Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Spåhr H, et al. Proc Natl Acad Sci U S A, 2001 Oct 9. PMID 11572939, Free PMC Article
    3. Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. Spåhr H, et al. J Biol Chem, 2000 Jan 14. PMID 10625684
    4. Core Mediator structure at 3.4 Å extends model of transcription initiation complex. Nozawa K, et al. Nature, 2017 May 11. PMID 28467824
    5. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Egan ED, et al. RNA, 2014 Jun. PMID 24713849, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables transcription coactivator activity IC
    Inferred by Curator
    more info
    		 PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription initiation by RNA polymerase II EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    mediator complex subunit Med4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3517461..3519089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022381.3 → NP_596462.1  mediator complex subunit Med4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596462.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y821
      Conserved Domains (1) summary
      pfam10018
      Location:41 → 153
      Med4; Vitamin-D-receptor interacting Mediator subunit 4
    Nucleotide Protein
    Heading Accession and Version

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