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    rga1 Rho-type GTPase-activating protein Rga1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541022, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rga1
    Official Full Name
    Rho-type GTPase-activating protein Rga1
    Primary source
    PomBase:SPBC3F6.05
    Locus tag
    SPOM_SPBC3F6.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rga1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (4196047..4200033)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glucosyltransferase Alg6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of GTPase-activating proteins for the function of the Rho-family small GTPases in the fission yeast Schizosaccharomyces pombe. Nakano K, et al. Genes Cells, 2001 Dec. PMID 11737264
    2. Pom1 DYRK regulates localization of the Rga4 GAP to ensure bipolar activation of Cdc42 in fission yeast. Tatebe H, et al. Curr Biol, 2008 Mar 11. PMID 18328707, Free PMC Article
    3. Rgf1p is a specific Rho1-GEF that coordinates cell polarization with cell wall biogenesis in fission yeast. García P, et al. Mol Biol Cell, 2006 Apr. PMID 16421249, Free PMC Article
    4. Rho1-GEFs Rgf1 and Rgf2 are involved in formation of cell wall and septum, while Rgf3 is involved in cytokinesis in fission yeast. Mutoh T, et al. Genes Cells, 2005 Dec. PMID 16324155
    5. Feedback regulation of SIN by Etd1 and Rho1 in fission yeast. Alcaide-Gavilán M, et al. Genetics, 2014 Feb. PMID 24336750, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTPase activator activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables GTPase activator activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell wall organization or biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex of cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell division site HDA PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in division septum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Rho-type GTPase-activating protein Rga1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4196047..4200033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023763.3 → NP_596743.1  Rho-type GTPase-activating protein Rga1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596743.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43052
      Conserved Domains (4) summary
      cd09391
      Location:116 → 172
      LIM1_Lrg1p_like; The first LIM domain of Lrg1p, a LIM and RhoGap domain containing protein
      cd09392
      Location:180 → 232
      LIM2_Lrg1p_like; The second LIM domain of Lrg1p, a LIM and RhoGap domain containing protein
      cd04397
      Location:835 → 1044
      RhoGAP_fLRG1; RhoGAP_fLRG1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of fungal LRG1-like proteins. Yeast Lrg1p is required for efficient cell fusion, and mother-daughter cell separation, possibly through acting as a RhoGAP specifically ...
      cl02475
      Location:485 → 539
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    Nucleotide Protein
    Heading Accession and Version

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