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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855109, updated on 10-Oct-2024

    Summary

    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000004690
    Locus tag
    YMR085W
    See related
    AllianceGenome:SGD:S000004690; FungiDB:YMR085W; VEuPathDB:YMR085W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in several processes, including UDP-N-acetylglucosamine metabolic process; fructose 6-phosphate metabolic process; and fungal-type cell wall chitin biosynthetic process. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12 and obesity. Orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (437491..438789)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase ADH3 Neighboring gene putative glutamine--fructose-6-phosphate transaminase Neighboring gene Seg1p Neighboring gene putative ADP-ribose 1''-phosphate phosphatase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables carbohydrate derivative binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in UDP-N-acetylglucosamine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in carbohydrate derivative metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chitin biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fructose 6-phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    NP_013802.1
    • hypothetical protein; YMR085W and adjacent ORF YMR084W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      437491..438789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182584.1NP_013802.1  TPA: uncharacterized protein YMR085W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013802.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8ZET8, D6VZQ8, P0CF18
      UniProtKB/TrEMBL
      G2WKD2
      Conserved Domains (1) summary
      COG0449
      Location:2428
      GlmS; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains [Cell wall/membrane/envelope biogenesis]