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    ght2 plasma membrane glucose/fructose:proton symporter Ght2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539977, updated on 22-Jun-2024

    Summary

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    Gene symbol
    ght2
    Gene description
    plasma membrane glucose/fructose:proton symporter Ght2
    Locus tag
    SPOM_SPBC4B4.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPBC4B4.08
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    Genomic context

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    See ght2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3427160..3429424)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ESCRT II complex subunit Vps25 Neighboring gene U1 snRNP-associated protein Usp102 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U1 snRNP-associated protein Prp39 Neighboring gene ncRNA Neighboring gene autophagy-associated protein Atg5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of hexose transporter genes in the views of the chronological life span and glucose uptake in fission yeast. Maruyama T, et al. J Gen Appl Microbiol, 2023 Mar 6. PMID 35781263
    2. Ght2⁺ is required for UDP-galactose synthesis from extracellular galactose by Schizosaccharomyces pombe. Matsuzawa T, et al. Appl Microbiol Biotechnol, 2013 Jun. PMID 23254763
    3. Mechanisms of expression and translocation of major fission yeast glucose transporters regulated by CaMKK/phosphatases, nuclear shuttling, and TOR. Saitoh S, et al. Mol Biol Cell, 2015 Jan 15. PMID 25411338, Free PMC Article
    4. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article
    5. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables carbohydrate:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables galactose transmembrane transporter activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbohydrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in galactose import across plasma membrane EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in glucose import IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plasma membrane glucose/fructose:proton symporter Ght2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3427160..3429424
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022344.3 → NP_596425.1  plasma membrane glucose/fructose:proton symporter Ght2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596425.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13346, O74969
      Conserved Domains (2) summary
      cd06174
      Location:14 → 456
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam00083
      Location:15 → 471
      Sugar_tr; Sugar (and other) transporter
    Nucleotide Protein
    Heading Accession and Version

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