U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    INP1 Inp1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855244, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    INP1
    Official Full Name
    Inp1p
    Primary source
    SGD:S000004817
    Locus tag
    YMR204C
    See related
    AllianceGenome:SGD:S000004817; FungiDB:YMR204C; VEuPathDB:YMR204C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein-macromolecule adaptor activity. Involved in peroxisome inheritance. Located in peroxisome. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See INP1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (670063..671325, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene C-8 sterol isomerase ERG2 Neighboring gene Tom40p Neighboring gene 6-phosphofructokinase subunit beta Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Characterization of survival and stress resistance in S. cerevisiae mutants affected in peroxisome inheritance and proliferation, Δinp1 and Δpex11. Scheckhuber CQ. Folia Microbiol (Praha), 2020 Apr. PMID 31273644
    2. Peroxisome retention involves Inp1-dependent peroxisome-plasma membrane contact sites in yeast. Krikken AM, et al. J Cell Biol, 2020 Oct 5. PMID 32805027, Free PMC Article
    3. An ER-peroxisome tether exerts peroxisome population control in yeast. Knoblach B, et al. EMBO J, 2013 Sep 11. PMID 23900285, Free PMC Article
    4. A dual function for Pex3p in peroxisome formation and inheritance. Munck JM, et al. J Cell Biol, 2009 Nov 16. PMID 19948495, Free PMC Article
    5. Yeast cells contain a heterogeneous population of peroxisomes that segregate asymmetrically during cell division. Choudhry SK, et al. J Cell Sci, 2018 Feb 7. PMID 29361529

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Pex3-Inp1 complex tethers yeast peroxisomes to the plasma membrane.
      Title: The Pex3-Inp1 complex tethers yeast peroxisomes to the plasma membrane.
    2. Peroxisome retention involves Inp1-dependent peroxisome-plasma membrane contact sites in yeast.
      Title: Peroxisome retention involves Inp1-dependent peroxisome-plasma membrane contact sites in yeast.
    3. Characterization of survival and stress resistance in S. cerevisiae mutants affected in peroxisome inheritance and proliferation, Deltainp1 and Deltapex11.
      Title: Characterization of survival and stress resistance in S. cerevisiae mutants affected in peroxisome inheritance and proliferation, Δinp1 and Δpex11.
    4. Inp1p acts as a molecular hinge between ER-bound Pex3p and peroxisomal Pex3p.
      Title: An ER-peroxisome tether exerts peroxisome population control in yeast.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peroxisome inheritance IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peroxisome inheritance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of intraperoxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisome HDA PubMed 
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Inp1p
    NP_013931.1
    • Peripheral membrane protein of peroxisomes; involved in peroxisomal inheritance; recruitment to peroxisomes is mediated by interaction with Pex3p at the peroxisomal membrane; Inp1p and Pex3p tether peroxisomes to plasma membrane

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      670063..671325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182711.1 → NP_013931.1  TPA: Inp1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013931.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZMR6, D6W029, Q03694
      UniProtKB/TrEMBL
      B3LM92, B5VPX2, C8ZF69, G2WKR0, N1NYZ4
      Conserved Domains (1) summary
      pfam12634
      Location:79 → 260
      Inp1; Inheritance of peroxisomes protein 1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03694.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools