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    csx1 RNA-binding protein Csx1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542151, updated on 22-Jun-2024

    Summary

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    Gene symbol
    csx1
    Gene description
    RNA-binding protein Csx1
    Locus tag
    SPOM_SPAC17A2.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Old locus tag
    SPAC17A2.09c
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    Genomic context

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    See csx1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3570007..3572345, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene spliceosome complex disassembly protein Ntr2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RNA binding protein Csx1 promotes sexual differentiation in Schizosaccharomyces pombe. Matia-Gonzalez AM, et al. PLoS One, 2012. PMID 22253882, Free PMC Article
    2. RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress. Rodríguez-Gabriel MA, et al. EMBO J, 2003 Dec 1. PMID 14633985, Free PMC Article
    3. RNA-binding protein Csx1 is phosphorylated by LAMMER kinase, Lkh1, in response to oxidative stress in Schizosaccharomyces pombe. Kang WH, et al. FEBS Lett, 2007 Jul 24. PMID 17612531
    4. Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress. Martín V, et al. Mol Biol Cell, 2006 Mar. PMID 16407405, Free PMC Article
    5. Cellular stress induces cytoplasmic RNA granules in fission yeast. Nilsson D, et al. RNA, 2011 Jan. PMID 21098141, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A novel mechanism of ste11+ mRNA positive regulation through the activity of Csx1, is presented.
      Title: The RNA binding protein Csx1 promotes sexual differentiation in Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 3'-UTR-mediated mRNA stabilization EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in 3'-UTR-mediated mRNA stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of gene expression EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulation of mRNA stability involved in response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasmic stress granule EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    NOT is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein Csx1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3570007..3572345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019666.2 → NP_594243.1  RNA-binding protein Csx1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594243.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13759, Q09331, Q09335
      Conserved Domains (5) summary
      TIGR01645
      Location:217 → 577
      half-pint; poly-U binding splicing factor, half-pint family
      COG0724
      Location:67 → 367
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12346
      Location:296 → 367
      RRM3_NGR1_NAM8_like; RNA recognition motif 3 in yeast negative growth regulatory protein NGR1 (RBP1), yeast protein NAM8 and similar proteins
      cd12611
      Location:86 → 168
      RRM1_NGR1_NAM8_like; RNA recognition motif 1 in yeast negative growth regulatory protein NGR1, yeast protein NAM8 and similar proteins
      cd12613
      Location:181 → 260
      RRM2_NGR1_NAM8_like; RNA recognition motif 2 in yeast negative growth regulatory protein NGR1, yeast protein NAM8 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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