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    vps8 WD repeat-containing protein Vps8 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542136, updated on 18-Sep-2024

    Summary

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    Official Symbol
    vps8
    Official Full Name
    WD repeat-containing protein Vps8
    Primary source
    PomBase:SPAC17A2.06c
    Locus tag
    SPOM_SPAC17A2.06C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See vps8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3562948..3566829, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene fumerate reductase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene spliceosome complex disassembly protein Ntr2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Abo1 is required for the H3K9me2 to H3K9me3 transition in heterochromatin. Dong W, et al. Sci Rep, 2020 Apr 8. PMID 32269268, Free PMC Article
    2. The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast. Fontebasso Y, et al. DNA Repair (Amst), 2013 Dec. PMID 24192486, Free PMC Article
    3. A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors. Chen Z, et al. G3 (Bethesda), 2012 Oct. PMID 23050226, Free PMC Article
    4. Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Dixon SJ, et al. Proc Natl Acad Sci U S A, 2008 Oct 28. PMID 18931302, Free PMC Article
    5. Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species. Beltrao P, et al. PLoS Biol, 2009 Jun 16. PMID 19547744, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables zinc ion binding NAS
    Non-traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    involved_in endosomal vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in late endosome to vacuole transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein targeting to vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of CORVET complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi apparatus HDA PubMed 
    part_of HOPS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm HDA PubMed 
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WD repeat-containing protein Vps8

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3562948..3566829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019663.2 → NP_594240.1  WD repeat-containing protein Vps8 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594240.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13756
      Conserved Domains (2) summary
      pfam12816
      Location:575 → 758
      Vps8; Golgi CORVET complex core vacuolar protein 8
      cl02567
      Location:96 → 184
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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