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    rad15 transcription factor TFIIH complex subunit Rad15 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542203, updated on 10-Jul-2024

    Summary

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    Gene symbol
    rad15
    Gene description
    transcription factor TFIIH complex subunit Rad15
    Locus tag
    SPOM_SPAC1D4.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rad5; rhp3
    Old locus tag
    SPAC1D4.12
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    Genomic context

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    See rad15 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (664348..667647)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene dual-specificity Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MAP kinase kinase Byr1 Neighboring gene THO complex subunit Tho2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Schizosaccharomyces pombe rhp3+ gene required for DNA repair and cell viability is functionally interchangeable with the RAD3 gene of Saccharomyces cerevisiae. Reynolds PR, et al. Nucleic Acids Res, 1992 May 11. PMID 1534406, Free PMC Article
    2. Cloning and characterisation of the S. pombe rad15 gene, a homologue to the S. cerevisiae RAD3 and human ERCC2 genes. Murray JM, et al. Nucleic Acids Res, 1992 Jun 11. PMID 1319571, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 5'-3' DNA helicase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables ATP binding IC
    Inferred by Curator
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II general transcription initiation factor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables damaged DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleotide-excision repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of mitotic recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase II promoter EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    part_of nucleotide-excision repair factor 3 complex IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIIH core complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of transcription factor TFIIH holo complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transcription factor TFIIH complex subunit Rad15
    NP_593025.1
    • transcription factor TFIIH complex DNA helicase (human ERCC2) subunit Rad15

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      664348..667647
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018424.3 → NP_593025.1  transcription factor TFIIH complex subunit Rad15 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593025.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P26659
      Conserved Domains (4) summary
      smart00488
      Location:8 → 279
      DEXDc2; DEAD-like helicases superfamily
      smart00491
      Location:541 → 685
      HELICc2; helicase superfamily c-terminal domain
      TIGR00604
      Location:7 → 707
      rad3; DNA repair helicase (rad3)
      pfam06777
      Location:268 → 412
      HBB; Helical and beta-bridge domain
    Nucleotide Protein
    Heading Accession and Version

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