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    VPS71 Vps71p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854966, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VPS71
    Official Full Name
    Vps71p
    Primary source
    SGD:S000004505
    Locus tag
    YML041C
    See related
    AllianceGenome:SGD:S000004505; FungiDB:YML041C; VEuPathDB:YML041C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SWC6
    Summary
    Enables nucleosome binding activity. Involved in histone exchange. Located in nucleus. Part of Swr1 complex. Orthologous to human ZNHIT1 (zinc finger HIT-type containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See VPS71 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (194913..195755, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Rrn11p Neighboring gene carnitine O-acetyltransferase CAT2 Neighboring gene tRNA-Pro Neighboring gene gag protein Neighboring gene gag-pol fusion protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory. Halley JE, et al. PLoS Biol, 2010 Jun 22. PMID 20582323, Free PMC Article
    2. The essential function of Swc4p - a protein shared by two chromatin-modifying complexes of the yeast Saccharomyces cerevisiae - resides within its N-terminal part. Miciałkiewicz A, et al. Acta Biochim Pol, 2008. PMID 18726008
    3. Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Emre NC, et al. Mol Cell, 2005 Feb 18. PMID 15721261
    4. Maintenance of heterochromatin boundary and nucleosome composition at promoters by the Asf1 histone chaperone and SWR1-C chromatin remodeler in Saccharomyces cerevisiae. Lu PY, et al. Genetics, 2014 May. PMID 24578349, Free PMC Article
    5. The roles of thiol oxidoreductases in yeast replicative aging. Hacioglu E, et al. Mech Ageing Dev, 2010 Nov-Dec. PMID 20934449, Free PMC Article

    See all (103) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleosome binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein targeting to vacuole HMP PubMed 
    Component Evidence Code Pubs
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Swr1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Vps71p
    NP_013671.1
    • Nucleosome-binding component of the SWR1 complex; SWR1 exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      194913..195755 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182399.1 → NP_013671.1  TPA: Vps71p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013671.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZD4, Q03433
      UniProtKB/TrEMBL
      A6ZM24, B3LLL4, B5VP89, C7GT68, C8ZEG6, G2WK14, N1NZ15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q03433.1

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