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    apl3 AP-2 adaptor complex subunit Alp3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541162, updated on 18-Sep-2024

    Summary

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    Official Symbol
    apl3
    Official Full Name
    AP-2 adaptor complex subunit Alp3
    Primary source
    PomBase:SPBC691.03c
    Locus tag
    SPOM_SPBC691.03C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See apl3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1424228..1427447, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene lipoate-protein ligase A Neighboring gene peroxin pas4 Neighboring gene ncRNA Neighboring gene palmitoyltransferase Pfa5 Neighboring gene RINT1 family protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The AP-2 complex is required for proper temporal and spatial dynamics of endocytic patches in fission yeast. de León N, et al. Mol Microbiol, 2016 May. PMID 26749213
    2. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article
    3. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
    4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    5. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables clathrin adaptor activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables clathrin adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in clathrin-dependent endocytosis EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in clathrin-dependent endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of AP-2 adaptor complex EXP
    Inferred from Experiment
    more info
    		 PubMed 
    part_of AP-2 adaptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cell cortex HDA PubMed 
    is_active_in cell cortex of cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in clathrin-coated pit EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    AP-2 adaptor complex subunit Alp3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1424228..1427447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021491.3 → NP_595595.1  AP-2 adaptor complex subunit Alp3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595595.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13623, O13624, Q9C0W7
      Conserved Domains (3) summary
      smart00809
      Location:654 → 753
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:25 → 578
      Adaptin_N; Adaptin N terminal region
      pfam02296
      Location:759 → 868
      Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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